Toll Like Receptors (Tl Rs) Sign Video
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Named for the Toll protein family discovered in Drosophila, Toll-like receptors occur on cell membranes of vertebrates. When activated by binding a microbe, they signal the cell to synthesize an appropriate antimicrobial peptide. Recognizing patterns rather than specific molecular configurations, they are a vital part of innate immune defenses.
Source: Hickman, C.P., et al. 2011. Integrated Principles of Zoology. Fifteenth Edition. McGraw-Hill Higher Education.
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