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Hemoglobin

  • Definition: A multimeric globular protein containing a heme prosthetic group that readily binds oxygen as a result of allosteric changes in proximal and distal histidine residues. Hemoglobin is found in nearly all mammals, and it has a low affinity for oxygen, as opposed to the structurally related myoglobin. Hemoglobin's multimeric structure allows it to participate in cooperative binding.

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