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Definition: In eukaryotes, a DNA molecule that contains genes in linear order to which numerous proteins are bound and that has a telomere at each end and a centromeres. In prokaryotes, the DNA is associated with fewer proteins, lacks telomers and a centromeres, and is often circular. In viruses, the chromosome is DNA or RNA, single strained or double-stranded, linear or circular, and often free of bound proteins.
Source: Essential Genetics: A Genomics Perspective (2006) 4th Ed.